PIEZO2 polyclonal antibody
Product Specifications
Background
The protein encoded by this gene contains more than thirty transmembrane domains and likely functions as part of mechanically-activated (MA) cation channels. These channels serve to connect mechanical forces to biological signals. The encoded protein quickly adapts MA currents in somatosensory neurons. Defects in this gene are a cause of type 5 distal arthrogryposis. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
C18orf30; C18orf58; FAM38B; Piezo-type mechanosensitive ion channel component 2; Protein FAM38B
Swiss Prot
Q9H5I5
Reactivity
Human
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the Central region of human PIEZO2.
Conjugation
Unconjugated
Applications
WB
Dilution
WB,1:500 - 1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 280 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
PIEZO2 polyclonal antibody detects endogenous levels of PIEZO2 protein.
Applications Notes
Western blot analysis of PIEZO2 expression in HepG2 (A), A549 (B) whole cell lysates.
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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