SRGAP2 polyclonal antibody

Product Specifications

Background

This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

SRGAP2; ARHGAP34; FNBP2; SRGAP2A; SRGAP3

Swiss Prot

O75044

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein of human SRGAP2 (NP_056141.2) .

Conjugation

Unconjugated

Applications

Dilution

WB,1:500 - 1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .