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PDE8B polyclonal antibody

Product Specifications

Background

The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD) . Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2010]

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

ADSD; PPNAD3; PDE8B

Swiss Prot

O95263

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human PDE8B (NP_003710.1) .

Conjugation

Unconjugated

Applications

WB

Dilution

WB,1:500 - 1:2000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

Refer to figures

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Unmodification

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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