AKT2 polyclonal antibody

Product Specifications

Background

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

AKT2; HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA

Swiss Prot

P31751

Reactivity

Human, Mouse, Rat, Monkey

Immunogen

A synthetic peptide of human AKT2 (NP_001617.1) .

Conjugation

Unconjugated

Applications

WB, IHC, IF/ICC, IP, ChIP

Dilution

WB,1:500 - 1:2000|IHC,1:50 - 1:100|IF/ICC,1:50 - 1:100|IP,1:20 - 1:50|ChIP,1:20 - 1:100

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .