SETD1A polyclonal antibody

Product Specifications

Background

The protein encoded by this gene is a component of a histone methyltransferase (HMT) complex that produces mono-, di-, and trimethylated histone H3 at Lys4. Trimethylation of histone H3 at lysine 4 (H3K4me3) is a chromatin modification known to generally mark the transcription start sites of active genes. The protein contains SET domains, a RNA recognition motif domain and is a member of the class V-like SAM-binding methyltransferase superfamily.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Set1; KMT2F; Set1A; SETD1A; SET1A

Swiss Prot

O15047

Reactivity

Human, Rat

Immunogen

A synthetic peptide of human SETD1A (NP_055527.1) .

Conjugation

Unconjugated

Applications

IF/ICC

Dilution

IF/ICC,1:20 - 1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .