SIRT4 polyclonal antibody
Product Specifications
Background
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
SIRT4; SIR2L4; sirtuin 4
Swiss Prot
Q9Y6E7
Reactivity
Human
Immunogen
Recombinant fusion protein of human SIRT4 (NP_036372.1) .
Conjugation
Unconjugated
Applications
IF/ICC
Dilution
IF/ICC,1:50 - 1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Unmodification
Applications Notes
Immunofluorescence analysis of U2OS cells using SIRT4 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Host or Source
Rabbit
CAS Number
9007-83-4
Available Sizes
Curated Selection
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