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SIRT4 polyclonal antibody

Product Specifications

Background

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

SIRT4; SIR2L4; sirtuin 4

Swiss Prot

Q9Y6E7

Reactivity

Human

Immunogen

Recombinant fusion protein of human SIRT4 (NP_036372.1) .

Conjugation

Unconjugated

Applications

IF/ICC

Dilution

IF/ICC,1:50 - 1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Unmodification

Applications Notes

Immunofluorescence analysis of U2OS cells using SIRT4 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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