KIF7 polyclonal antibody

Product Specifications

Background

This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

KIF7; ACLS; AGBK; HLS2; JBTS12; UNQ340

Swiss Prot

Q2M1P5

Reactivity

Human

Immunogen

Recombinant fusion protein of human KIF7 (NP_940927.2) .

Conjugation

Unconjugated

Applications

Dilution

WB,1:200 - 1:2000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .