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DNAJC24 polyclonal antibody

Product Specifications

Background

Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610) . This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]) .[supplied by OMIM, Mar 2008]

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

DNAJC24; DPH4; JJJ3; ZCSL3

Swiss Prot

Q6P3W2

Reactivity

Mouse

Immunogen

Recombinant fusion protein of human DNAJC24 (NP_859057.4) .

Conjugation

Unconjugated

Applications

WB

Dilution

WB,1:200 - 1:2000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

17kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Unmodification

Host or Source

Rabbit

Available Sizes

Curated Selection

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