CDCA7L polyclonal antibody

Product Specifications

Background

Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

CDCA7L; JPO2; R1; RAM2

Swiss Prot

Q96GN5

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human CDCA7L (NP_061189.2) .

Conjugation

Unconjugated

Applications

Dilution

WB,1:200 - 1:2000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .