CLSTN1 polyclonal antibody

Product Specifications

Background

This gene is a member of the calsyntenin family, a subset of the cadherin superfamily. The encoded transmembrane protein, also known as alcadein-alpha, is thought to bind to kinesin-1 motors to mediate the axonal anterograde transport of certain types of vesicle. Amyloid precursor protein (APP) is trafficked via these vesicles and so this protein is being investigated to see how it might contribute to the mechanisms underlying Alzheimer's disease. Alternative splicing results in multiple transcript variants.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

CLSTN1; ALC-ALPHA; CDHR12; CST-1; CSTN1; PIK3CD; XB31alpha; alcalpha1; alcalpha2

Swiss Prot

O94985

Reactivity

Mouse, Rat

Immunogen

Recombinant fusion protein of human CLSTN1 (NP_055759.3) .

Conjugation

Unconjugated

Applications

WB, IF/ICC

Dilution

WB,1:200 - 1:2000|IF/ICC,1:50 - 1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .