NKIRAS1 polyclonal antibody
Product Specifications
Background
Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
NKIRAS1; KBRAS1; kappaB-Ras1
Swiss Prot
Q9NYS0
Reactivity
Mouse, Rat
Immunogen
Recombinant fusion protein of human NKIRAS1 (NP_065078.1) .
Conjugation
Unconjugated
Applications
WB, IF/ICC
Dilution
WB,1:500 - 1:2000|IF/ICC,1:50 - 1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
22kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Unmodification
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6192144-01 0.1 mL
RABEP1 (Rab GTPase-binding Effector Protein 1, Rabaptin-4, Rabaptin-5, Rabaptin-5alpha, Renal Carcinoma Antigen NY-REN-17, RAB5EP, RABPT5, RABPT5A) (MaxLight 405)
Sign In for Pricing
View Details MBS6192144-02 5x 0.1 mL
RABEP1 (Rab GTPase-binding Effector Protein 1, Rabaptin-4, Rabaptin-5, Rabaptin-5alpha, Renal Carcinoma Antigen NY-REN-17, RAB5EP, RABPT5, RABPT5A) (MaxLight 405)
Sign In for Pricing
View Details