What is the catalog number for CRACR2A polyclonal antibody?

The catalog number for CRACR2A polyclonal antibody is BS75484.

What sizes are available for CRACR2A polyclonal antibody?

CRACR2A polyclonal antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does CRACR2A polyclonal antibody come in?

CRACR2A polyclonal antibody is available in 2 different pack sizes.

Is CRACR2A polyclonal antibody in stock?

CRACR2A polyclonal antibody is currently made to order / not held in immediate stock. Contact us for lead time.

CRACR2A polyclonal antibody

Product Specifications

Background

[Isoform 1]: Ca (2+-binding protein that plays a key role in store-operated Ca (2+ entry (SOCE in T-cells by regulating CRAC channel activation. Acts as a cytoplasmic calcium-sensor that facilitates the clustering of ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca (2+ concentration. It thereby regulates CRAC channel activation, including translocation and clustering of ORAI1 and STIM1. Upon increase of cytoplasmic Ca (2+ resulting from opening of CRAC channels, dissociates from ORAI1 and STIM1, thereby destabilizing the ORAI1-STIM1 complex.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

CRACR2A; EFCAB4B

Swiss Prot

Q9BSW2

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein of human CRACR2A (NP_001138430.1) .

Conjugation

Unconjugated

Applications

WB, IHC

Dilution

WB,1:500 - 1:2000|IHC,1:50 - 1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .