TESC polyclonal antibody

Product Specifications

Background

Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na (+/H (+ exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane. Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. Inhibits the phosphatase activity of calcineurin.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

TESC; CHP3; TSC; tescalcin

Swiss Prot

Q96BS2

Reactivity

Mouse

Immunogen

Recombinant fusion protein of human TESC (NP_060369.3) .

Conjugation

Unconjugated

Applications

Dilution

WB,1:1000 - 1:2000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .