U2AF1 polyclonal antibody

Product Specifications

Background

This gene belongs to the splicing factor SR family of genes. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. Alternatively spliced transcript variants encoding different isoforms have been identified.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

U2AF1; FP793; RN; RNU2AF1; U2AF35; U2AFBP

Swiss Prot

Q01081

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human U2AF1 (NP_006749.1) .

Conjugation

Unconjugated

Applications

WB, IHC, IP

Dilution

WB,1:500 - 1:2000|IHC,1:100 - 1:200|IP,1:50 - 1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .