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CWC22 polyclonal antibody

Product Specifications

Background

Required for pre-mRNA splicing as component of the spliceosome. Promotes exon-junction complex (EJC assembly. Hinders EIF4A3 from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs. Through its role in EJC assembly, required for nonsense-mediated mRNA decay.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

CWC22; EIF4GL; NCM; fSAPb

Swiss Prot

Q9HCG8

Reactivity

Mouse

Immunogen

Recombinant fusion protein of human CWC22 (NP_065994.1) .

Conjugation

Unconjugated

Applications

WB

Dilution

WB,1:1000 - 1:2000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

110kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Unmodification

Host or Source

Rabbit

Available Sizes

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