DKC1 polyclonal antibody
Product Specifications
Background
This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs) . This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
DKC1; CBF5; DKC; DKCX; NAP57; NOLA4; XAP101
Swiss Prot
O60832
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human DKC1 (NP_001354.1) .
Conjugation
Unconjugated
Applications
WB, IHC, IF/ICC
Dilution
WB,1:500 - 1:2000|IHC,1:50 - 1:100|IF/ICC,1:50 - 1:100
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
57kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Unmodification
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
bs-9891R-BF647 100 µL
NDST1 Polyclonal Antibody, AbBy Fluor™ 647 Conjugated
Sign In for Pricing
View Details 
DLR-Bcl2L-Mu-01 48 Tests
Mouse B-Cell CLL/Lymphoma 2 Like Protein (Bcl2L) ELISA Kit
Sign In for Pricing
View Details DLR-Bcl2L-Mu-02 96 Tests
Mouse B-Cell CLL/Lymphoma 2 Like Protein (Bcl2L) ELISA Kit
Sign In for Pricing
View Details