Palladium (II) acetylacetonate

Palladium (II) acetylacetonate is a metal-organic complex. Palladium (II) acetylacetonate upregulates the expression of GRP78, ATF-4, XBP-1, CHOP, and phosphorylated c-Jun. Palladium (II) acetylacetonate induces Apoptosis. Palladium (II) acetylacetonate has anticancer effects against non-small cell lung cancer, gastric cancer, leukemia, and cervical cancer[1][2][3].

Product Specifications

CAS Number

[14024-61-4]

Product Name Alternative

Palladium (II) 2,4-pentanedionate; Pd (acac) 2

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Biochemical Assay Reagents; Eukaryotic Initiation Factor (eIF) ; HSP; IRE1; JNK

Type

Biochemical Assay Reagents

Related Pathways

Apoptosis; Cell Cycle/DNA Damage; MAPK/ERK Pathway; Metabolic Enzyme/Protease; Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/palladium-acetylacetonate.html

Purity

98.2

Solubility

DMSO : 2 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CC(/C=C([O-])/C)=O.[Pd+2].[2]

Molecular Formula

C10H14O4Pd

Molecular Weight

304.62

Precautions

H302, H315, H319, H335

References & Citations

[2]Wang Y, et al. An oxygen-chelate complex, palladium bis-acetylacetonate, induces apoptosis in H460 cells via endoplasmic reticulum stress pathway rather than interacting with DNA. J Med Chem. 2013 Dec 12;56 (23) :9601-11.|[3]Özkar S, et al. Palladium (0) Nanoparticle Formation, Stabilization, and Mechanistic Studies: Pd (acac) ₂ as a Preferred Precursor, [Bu₄N]₂HPO₄ Stabilizer, plus the Stoichiometry, Kinetics, and Minimal, Four-Step Mechanism of the Palladium Nanoparticle Formation and Subsequent Agglomeration Reactions. Langmuir. 2016 Apr 19;32 (15) :3699-716. |[1]Cominos V, et al. Sublimation and deposition behaviour of palladium (II) acetylacetonate. The European Physical Journal-Applied Physics, 2001, 15 (1) : 23-33.