ULBP1 polyclonal antibody

Product Specifications

Background

The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

ULBP1; N2DL-1; NKG2DL1; RAET1I

Swiss Prot

Q9BZM6

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein of human ULBP1 (NP_079494.1) .

Conjugation

Unconjugated

Applications

WB, IHC

Dilution

WB,1:1000 - 1:2000|IHC,1:50 - 1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .