PODXL polyclonal antibody

Product Specifications

Background

This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

PODXL; Gp200; PC; PCLP; PCLP-1

Swiss Prot

O00592

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human PODXL (NP_005388.2) .

Conjugation

Unconjugated

Applications

WB, IF/ICC

Dilution

WB,1:1000 - 1:2000|IF/ICC,1:100 - 1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .