Ezrin polyclonal antibody

Product Specifications

Background

The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

CVIL; CVL; HEL-S-105; VIL2; EZR; Ezrin; ezrin

Swiss Prot

P15311

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human Ezrinin (NP_003370.2) .

Conjugation

Unconjugated

Applications

WB, IF/ICC, IP

Dilution

WB,1:500 - 1:2000|IF/ICC,1:50 - 1:100|IP,1:50 - 1:100

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .