Phospho-MAPKAPK-2/MK2-T334 polyclonal antibody
Product Specifications
Background
This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene.
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
MAPKAPK2; MAPKAP-K2; MK-2; MK2
Swiss Prot
P49137
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic phosphorylated peptide around T334 of human MAPKAPK2 (NP_116584.2?) .
Conjugation
Unconjugated
Applications
IHC
Dilution
IHC,1:50 - 1:100
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Phosphorylated
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Phosphorylated
Applications Notes
Immunohistochemistry of paraffin-embedded Mouse kidney using Phospho-MAPKAPK-2/MK2-T334 antibody at dilution of 1:200 .Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Host or Source
Rabbit
CAS Number
9007-83-4
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
22593141 1x10<sup>6</sup> cells/1.0ml
GPR88 CRISPR Knock Out 293T Cell Line (Human)
Ask
View Details 
