HMGB2 monoclonal antibody
Product Specifications
Background
DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V (D) J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS) .
CAS Number
9007-83-4
Structure Composition
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Product Name Alternative
HMG 2; HMG B2; HMG-2; HMG2; HMGB2
Swiss Prot
P26583
Reactivity
Human, Mouse, Rat, Hamster
Immunogen
A synthetic peptide of human HMGB2
Conjugation
Unconjugated
Applications
WB, IHC-F, IHC-P, ICC/IF, IP
Dilution
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Purity
Affinity Purified
Modification
Unmodified
Molecular Weight
Calculated MW: 24 kDa; Observed MW: 24 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Immunocytochemistry analysis of HMGB2 in Jurkat using HMGB2 antibody, and DAPI.
Host or Source
Rabbit
Available Sizes
Curated Selection
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