Phospho-delta 1 Catenin (Ser268) monoclonal antibody
Product Specifications
Background
Catenin δ-1 (p120 catenin) has an amino-terminal coiled-coil domain followed by a regulatory domain containing multiple phosphorylation sites and a central Armadillo repeat domain of ten linked 42-amino acid repeats. The carboxy-terminal tail has no known function. Catenin δ-1 fulfills critical roles in the regulation of cell-cell adhesion as it regulates E-cadherin turnover at the cell surface to determine the level of E-cadherin available for cell-cell adhesion.
CAS Number
9007-83-4
Structure Composition
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Product Name Alternative
CAS; p120; BCDS2; CTNND; P120CAS; P120CTN; p120 (CAS) ; p120 (CTN)
Swiss Prot
O60716
Reactivity
Human, Mouse
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Ser268 of human delta 1 Catenin/CAS
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1/500-1/1000
Purity
Affinity Purified
Modification
Phosphorylated
Molecular Weight
Calculated MW: 108 kDa; Observed MW: 100 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of Phospho-delta 1 Catenin/CAS in A549, MCF-7, U251, C2C12 lysates using Phospho-delta 1 Catenin antibody.
Host or Source
Rabbit
Available Sizes
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