PRAME monoclonal antibody

Product Specifications

Background

Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis.

CAS Number

9007-83-4

Structure Composition

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Product Name Alternative

MAPE; OIP4; CT130; OIP-4

Swiss Prot

P78395

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human PRAME

Conjugation

Unconjugated

Applications

WB, IHC-P, IP

Dilution

WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20

Purity

Affinity Purified

Modification

Unmodified

Molecular Weight

Calculated MW: 58 kDa; Observed MW: 58 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Immunohistochemistry analysis of paraffin-embedded mouse testis using PRAME antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.