Nibrin monoclonal antibody
Product Specifications
Background
NBS1 is a member of the MRE11/RAD50 double-strand break repair complex. Involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. Mutation results in the Nijmegen breakage syndrome (NBS), an autosomal recessive chromosomal instability syndrome.
CAS Number
9007-83-4
Structure Composition
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Product Name Alternative
NBN; NBS; NBS1; P95; Nibrin; Cell cycle regulatory protein p95; Nijmegen breakage syndrome protein 1
Swiss Prot
O60934
Reactivity
Human
Immunogen
A synthetic peptide of human p95 NBS1
Conjugation
Unconjugated
Applications
WB, ICC/IF, IP
Dilution
WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Purity
Affinity Purified
Modification
Unmodified
Molecular Weight
Calculated MW: 85 kDa; Observed MW: 95 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of p95/NBS1 in Hela lysates using Nibrin antibody.
Host or Source
Rabbit
Available Sizes
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