Macro H2A.1 monoclonal antibody
Product Specifications
Background
Involved in stable X chromosome inactivation. Inhibits the binding of transcription factors and interferes with the activity of remodeling SWI/SNF complexes. Inhibits histone acetylation by EP300 and recruits class I HDACs, which induces an hypoacetylated state of chromatin.
CAS Number
9007-83-4
Structure Composition
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Product Name Alternative
H2A.y; H2A/y; mH2A1; H2AF12M; MACROH2A1.1; macroH2A1.2
Swiss Prot
O75367
Reactivity
Mouse, Rat
Immunogen
A synthetic peptide of human macroH2A.1
Conjugation
Unconjugated
Applications
WB, ICC/IF
Dilution
WB: 1/500-1/1000 IF: 1/50-1/200
Purity
Affinity Purified
Modification
Unmodified
Molecular Weight
Calculated MW: 40 kDa; Observed MW: 40 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of macroH2A.1 in rat Brain, C6, 3T3 lysates using Macro H2A.1 antibody.
Host or Source
Rabbit
Available Sizes
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