Islet 1 monoclonal antibody
Product Specifications
Background
ISL1 (ISL1 transcription factor, LIM/homeodomain) is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. It is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry.
CAS Number
9007-83-4
Structure Composition
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Product Name Alternative
ISL1; Insulin gene enhancer protein ISL-1; Islet-1
Swiss Prot
P61371
Reactivity
Human, Rat
Immunogen
Recombinant protein of human Islet 1
Conjugation
Unconjugated
Applications
WB, IHC-P, IP
Dilution
WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
Purity
Affinity Purified
Modification
Unmodified
Molecular Weight
Calculated MW: 39 kDa; Observed MW: 39 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of Islet 1 in K562, rat Brain lysates using Islet 1 antibody.
Host or Source
Rabbit
Available Sizes
Curated Selection
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