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Phospho-IKB alpha (Ser36) monoclonal antibody

Product Specifications

Background

NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB, MIM 604495), which inactivate NF-kappa-B by trapping it in the cytoplasm.

Structure Composition

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Product Name Alternative

NFKBIA; IKBA; MAD3; NFKBI; NF-kappa-B inhibitor alpha; I-kappa-B-alpha; IkB-alpha; IkappaBalpha; Major histocompatibility complex enhancer-binding protein MAD3

Swiss Prot

P25963

Reactivity

Human, Mouse

Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Ser36 of human IKB alpha

Conjugation

Unconjugated

Applications

WB

Dilution

WB: 1/500-1/1000

Purity

Affinity Purified

Modification

Phosphorylated

Molecular Weight

Calculated MW: 36 kDa; Observed MW: 39 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot analysis of IKB alpha in K562, 3T3, Hela lysates using Phospho-IKB alpha antibody.

Host or Source

Rabbit

CAS Number

9007-83-4

Available Sizes

Curated Selection

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