Phospho-Dishevelled 2 (Ser143) monoclonal antibody
Product Specifications
Background
Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Participates both in canonical and non-canonical Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling.
CAS Number
9007-83-4
Structure Composition
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Product Name Alternative
DSH homolog 2
Swiss Prot
O14641
Reactivity
Human, Mouse
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Ser143 of human Dishevelled 2
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1/500-1/1000
Purity
Affinity Purified
Modification
Phosphorylated
Molecular Weight
Calculated MW: 79 kDa; Observed MW: 90-95 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of Dishevelled 2 in K562 lysates using Phospho-Dishevelled 2 antibody.
Host or Source
Rabbit
Available Sizes
Curated Selection
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