Phospho-CD3 zeta (Tyr142) monoclonal antibody
Product Specifications
Background
Defects in CD3D are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (T (-) /B (+) /NK (+) SCID) [MIM:608971]. A form of severe combined immunodeficiency (SCID), a genetically and clinically heterogeneous group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels.
CAS Number
9007-83-4
Structure Composition
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Product Name Alternative
CD247; CD3Z; T3Z; TCRZ; T-cell surface glycoprotein CD3 zeta chain; T-cell receptor T3 zeta chain; CD antigen CD247
Swiss Prot
P20963
Reactivity
Human
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Tyr142 of human CD3 zeta
Conjugation
Unconjugated
Applications
WB, IP
Dilution
WB: 1/500-1/1000 IP: 1/20
Purity
Affinity Purified
Modification
Phosphorylated
Molecular Weight
Calculated MW: 19 kDa; Observed MW: 19 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of Phospho-CD3 zeta in Jurkat lysates using Phospho-CD3 zeta antibody.
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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