Phospho-ATP Citrate Synthase (Thr447/Ser451) monoclonal antibody
Product Specifications
Background
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis.
CAS Number
9007-83-4
Structure Composition
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Product Name Alternative
ACLY; ATP-citrate synthase; ATP-citrate; pro-S-) -lyase; ACL; Citrate cleavage enzyme
Swiss Prot
P53396
Reactivity
Human
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Thr447/Ser451 of human ATP citrate lyase
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1/500-1/1000
Purity
Affinity Purified
Modification
Phosphorylated
Molecular Weight
Calculated MW: 121 kDa; Observed MW: 121 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of Phospho-ATP citrate lyase in K562 lysates using Phospho-ATP Citrate Synthase antibody.
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC040149-500 1x 500 µL
CD106 / VCAM1 (1.4C3), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC400806-500 1x 500 µL
TYRP1 (Tyrosinase Related Protein 1) (TA99), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC681461-100 1x 100 µL
CD45 / LCA (B-Cell Marker) (PTPRC/1461), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC402076-100 1x 100 µL
GFAP (Astrocyte & Neural Stem Cell Marker) (GFAP/2076), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details