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Phospho-Glutamate Receptor 1 (AMPA Subtype) (Ser845) monoclonal antibody

Product Specifications

Background

AMPA- (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid), kainate-, and NMDA- (N-methyl-D-aspartate) receptors are the three main families of ionotropic glutamate-gated ion channels. AMPA receptors (AMPARs) are comprised of four subunits (GluR 1-4), which assemble as homo- or hetero-tetramers to mediate the majority of fast excitatory transmissions in the central nervous system. AMPARs are implicated in synapse formation, stabilization, and plasticity.

CAS Number

9007-83-4

Structure Composition

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Product Name Alternative

GRIA1; GLUH1; GLUR1; Glutamate receptor 1; GluR-1; AMPA-selective glutamate receptor 1; GluR-A; GluR-K1; Glutamate receptor ionotropic; AMPA 1; GluA1

Swiss Prot

P42261

Reactivity

Human, Rat

Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Ser845 of human AMPA Receptor 1 (GluA1)

Conjugation

Unconjugated

Applications

WB

Dilution

WB: 1/500-1/1000

Purity

Affinity Purified

Modification

Phosphorylated

Molecular Weight

Calculated MW: 102 kDa; Observed MW: 102 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot analysis of Phospho-Glutamate Receptor 1 in U87-MG lysates using Phospho-Glutamate Receptor 1 antibody.

Host or Source

Rabbit

Available Sizes

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