Phospho-Smad3 (Ser423/425) monoclonal antibody
Product Specifications
Background
Smad3 transcription factor phosphorylated and activated by TGF-beta-type receptors. A receptor-regulated Smad (R-smad) . Binds directly to consensus DNA-binding elements in the promoters of target genes. In mouse required for establishemnt of the mucosal immune response and proper development of skeleton.
CAS Number
9007-83-4
Structure Composition
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Product Name Alternative
SMAD3; MADH3; Mothers against decapentaplegic homolog 3; MAD homolog 3; Mad3; Mothers against DPP homolog 3; hMAD-3; JV15-2; SMAD family member 3; SMAD 3; Smad3; hSMAD3
Swiss Prot
P84022
Reactivity
Human, Rat, Hamster
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Ser423/Ser425 of human Smad3
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1/500-1/1000
Purity
Affinity Purified
Modification
Phosphorylated
Molecular Weight
Calculated MW: 48 kDa; Observed MW: 52 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of Phospho-Smad3 in Jurkat, C6, CHO-K1, Hela lysates using Phospho-Smad3 antibody.
Host or Source
Rabbit
Available Sizes
Curated Selection
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