ERK1/2 monoclonal antibody
Product Specifications
Background
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.
CAS Number
9007-83-4
Structure Composition
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Product Name Alternative
MAPK3; ERK1; ERT2; ERK-1; PRKM3; P44ERK1; P44MAPK; HS44KDAP; HUMKER1A; p44-ERK1; p44-MAPK; MAPK1; ERK; p38; p40; p41; ERK2; ERT1; ERK-2; MAPK2; PRKM1; PRKM2; P42MAPK; p41mapk; p42-MAPK.
Swiss Prot
P27361/P28482
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human ERK2
Conjugation
Unconjugated
Applications
WB, ICC/IF, IP
Dilution
WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Purity
Affinity Purified
Modification
Unmodified
Molecular Weight
Calculated MW: 44,42 kDa; Observed MW: 44,42 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Immunocytochemistry analysis of ERK1/2 in K562 using ERK1/2 antibody, and DAPI.
Host or Source
Rabbit
Available Sizes
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