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CD130 polyclonal antibody

Product Specifications

Background

The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates the intracellular JAK-MAPK and JAK-STAT3 signaling pathways.

CAS Number

9007-83-4

Structure Composition

PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Product Name Alternative

Interleukin-6 receptor subunit beta , IL-6 receptor subunit beta, IL-6R subunit beta, IL-6R-beta, IL-6RB, CDw130

Swiss Prot

P40189

Reactivity

Human, Mouse

Immunogen

A synthesized peptide derived from human CD130/gp130

Conjugation

Unconjugated

Applications

WB, IHC-P

Dilution

WB: 1/500-1/1000 IHC: 1/50-1/100

Purity

Affinity Purified

Modification

Unmodified

Molecular Weight

Calculated MW: 104 kDa; Observed MW: 130-140kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot analysis of CD130 in 293T, COLO lysates using CD130 antibody.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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