CD130 polyclonal antibody
Product Specifications
Background
The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates the intracellular JAK-MAPK and JAK-STAT3 signaling pathways.
CAS Number
9007-83-4
Structure Composition
PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Product Name Alternative
Interleukin-6 receptor subunit beta , IL-6 receptor subunit beta, IL-6R subunit beta, IL-6R-beta, IL-6RB, CDw130
Swiss Prot
P40189
Reactivity
Human, Mouse
Immunogen
A synthesized peptide derived from human CD130/gp130
Conjugation
Unconjugated
Applications
WB, IHC-P
Dilution
WB: 1/500-1/1000 IHC: 1/50-1/100
Purity
Affinity Purified
Modification
Unmodified
Molecular Weight
Calculated MW: 104 kDa; Observed MW: 130-140kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of CD130 in 293T, COLO lysates using CD130 antibody.
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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