Phospho-Syk (Tyr323) polyclonal antibody
Product Specifications
Background
This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Structure Composition
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Product Name Alternative
SYK; Tyrosine-protein kinase SYK; Spleen tyrosine kinase; p72-Syk
Swiss Prot
P43405
Reactivity
Human
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Tyr323 of human Syk
Conjugation
Unconjugated
Applications
WB, IHC-F, IHC-P, ICC/IF, FC
Dilution
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 FC: 1/50-1/100
Purity
Affinity Purified
Modification
Phosphorylated
Molecular Weight
Calculated MW: 72 kDa; Observed MW: 72 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of Phospho-Syk in K562 lysates using Phospho-Syk antibody.
Host or Source
Rabbit
Available Sizes
Curated Selection
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