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Cytokeratin 18 polyclonal antibody

Product Specifications

Background

When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity) . Together with KRT8, is involved in interleukin-6 (IL-6) -mediated barrier protection.

CAS Number

9007-83-4

Structure Composition

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Product Name Alternative

CK18; CYK18; KRT18

Swiss Prot

P05784

Reactivity

Human

Immunogen

Recombinant protein of mouse Cytokeratin 18

Conjugation

Unconjugated

Applications

FC, ICC/IF, WB, IHC-P, IHC-F

Dilution

WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 FC: 1/50-1/100

Purity

Affinity Purified

Modification

Unmodified

Molecular Weight

Calculated MW: 48 kDa; Observed MW: 48 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot analysis of Keratin 18 in Hela, K562 lysates using Cytokeratin 18 antibody.

Host or Source

Rabbit

Available Sizes

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