CNOT7 polyclonal antibody
Product Specifications
Background
Has 3'-5' poly (A) exoribonuclease activity for synthetic poly (A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.
CAS Number
9007-83-4
Structure Composition
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Product Name Alternative
CCR4-associated factor 1; CAF-1
Swiss Prot
Q60809
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
A synthetic peptide of mouse CNOT7
Conjugation
Unconjugated
Applications
WB, IHC-P, FC, IP
Dilution
WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20 FC: 1/50-1/100
Purity
Affinity Purified
Modification
Unmodified
Molecular Weight
Calculated MW: 33 kDa; Observed MW: 33 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of CNOT7 in F9, C6, PC-12, 3T3, Raw264.7 lysates using CNOT7 antibody.
Host or Source
Rabbit
Available Sizes
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