OTC polyclonal antibody
Product Specifications
Background
This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.
CAS Number
9007-83-4
Structure Composition
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Product Name Alternative
OTCase; Ornithine carbamoyltransferase; mitochondrial; OCTD
Swiss Prot
P00480
Reactivity
Mouse, Rat
Immunogen
A synthetic peptide of human Ornithine Carbamoyltransferase
Conjugation
Unconjugated
Applications
WB, IHC-P, IP
Dilution
WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
Purity
Affinity Purified
Modification
Unmodified
Molecular Weight
Calculated MW: 40 kDa; Observed MW: 40 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of Ornithine Carbamoyltransferase/OTC in rat liver lysates using OTC antibody.
Host or Source
Rabbit
Available Sizes
Curated Selection
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