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DNA Nucleotidylexotransferase polyclonal antibody

Product Specifications

Background

Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Product Name Alternative

DNA nucleotidylexotransferase; DNTT; TDT; Terminal addition enzyme; Terminal deoxynucleotidyltransferase; Terminal transferase

Swiss Prot

P04053

Reactivity

Human

Immunogen

A synthesized peptide derived from human TDT

Conjugation

Unconjugated

Applications

WB, IHC-P

Dilution

WB: 1/500-1/1000 IHC: 1/50-1/100

Purity

Affinity Purified

Modification

Unmodified

Molecular Weight

Calculated MW: 59 kDa; Observed MW: 59 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot analysis of TDT in Jurkat lysates using DNA Nucleotidylexotransferase antibody.

Host or Source

Rabbit

Available Sizes

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