WDR5 polyclonal antibody
Product Specifications
Background
Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Product Name Alternative
WDR5; BIG3; WD repeat-containing protein 5; BMP2-induced 3-kb gene protein
Swiss Prot
P61964
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human WDR5
Conjugation
Unconjugated
Applications
WB, IHC-P, FC
Dilution
WB: 1/500-1/1000 IHC: 1/50-1/100 FC: 1/50-1/100
Purity
Affinity Purified
Modification
Unmodified
Molecular Weight
Calculated MW: 37 kDa; Observed MW: 37 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of WDR5 in HeLa lysates using WDR5 antibody.
Host or Source
Rabbit
Available Sizes
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