NF-KB p100 polyclonal antibody
Product Specifications
Background
Transcription factors of the nuclear factor κ B (NF-κB) /Rel family play a pivotal role in inflammatory and immune responses. NF-κB-activating agents can induce the phosphorylation of IκB proteins, targeting them for rapid degradation through the ubiquitin-proteasome pathway and releasing NF-κB to enter the nucleus where it regulates gene expression.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Product Name Alternative
NFKB2; LYT10; Nuclear factor NF-kappa-B p100 subunit; DNA-binding factor KBF2; H2TF1; Lymphocyte translocation chromosome 10 protein; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2; Oncogene Lyt-10; Lyt10
Swiss Prot
Q00653
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human NFkB p100 / p52
Conjugation
Unconjugated
Applications
WB, ICC/IF, IP
Dilution
WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Purity
Affinity Purified
Modification
Unmodified
Molecular Weight
Calculated MW: 97 kDa; Observed MW: 120,52 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of NF-KB p100 / p52 in Jurkat lysates; mouse heart lysates using NF-KB p100 antibody.
Host or Source
Rabbit
Available Sizes
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