USP13 polyclonal antibody
Product Specifications
Background
Mediates deubiquitination of BECN1, a key regulator of autophagy, leading to stabilize the PIK3C3/VPS34-containing complexes. Also deubiquitinates USP10, an essential regulator of p53/TP53 stability.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Product Name Alternative
Deubiquitinating enzyme 13; Isopeptidase T3; ISOT3; UBP13; USP13
Swiss Prot
Q92995
Reactivity
Human, Mouse
Immunogen
A synthesized peptide derived from human USP13
Conjugation
Unconjugated
Applications
WB, ICC/IF, IP, FC
Dilution
WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100
Purity
Affinity Purified
Modification
Unmodified
Molecular Weight
Calculated MW: 97 kDa; Observed MW: 97 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of USP13 in HepG2 lysates using USP13 antibody.
Host or Source
Rabbit
Available Sizes
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