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RAP80 polyclonal antibody

Product Specifications

Background

Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Plays a central role in the BRCA1-A complex by specifically binding 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs) .

CAS Number

9007-83-4

Structure Composition

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Product Name Alternative

RAP80; X2HRIP110

Swiss Prot

Q96RL1

Reactivity

Human

Immunogen

A synthesized peptide derived from human RAP80

Conjugation

Unconjugated

Applications

WB, IHC-P, ICC/IF

Dilution

WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Purity

Affinity Purified

Modification

Unmodified

Molecular Weight

Calculated MW: 80 kDa; Observed MW: 80 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot analysis of RAP80 in 293T lysates using RAP80 antibody.

Host or Source

Rabbit

Available Sizes

Curated Selection

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