HP1 gamma polyclonal antibody
Product Specifications
Background
Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR) . Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Product Name Alternative
CBX3; Chromobox protein homolog 3; HECH; Heterochromatin protein 1 homolog gamma; HP1 gamma; Modifier 2 protein
Swiss Prot
Q13185
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human HP1 gamma
Conjugation
Unconjugated
Applications
WB, IHC-P, IP, FC
Dilution
WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20 FC: 1/50-1/100
Purity
Affinity Purified
Modification
Unmodified
Molecular Weight
Calculated MW: 21 kDa; Observed MW: 24 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of HP1 gamma in HeLa lysates; NIH/3T3 lysates using HP1 gamma antibody.
Host or Source
Rabbit
Available Sizes
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