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HP1 gamma polyclonal antibody

Product Specifications

Background

Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR) . Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Product Name Alternative

CBX3; Chromobox protein homolog 3; HECH; Heterochromatin protein 1 homolog gamma; HP1 gamma; Modifier 2 protein

Swiss Prot

Q13185

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human HP1 gamma

Conjugation

Unconjugated

Applications

WB, IHC-P, IP, FC

Dilution

WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20 FC: 1/50-1/100

Purity

Affinity Purified

Modification

Unmodified

Molecular Weight

Calculated MW: 21 kDa; Observed MW: 24 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot analysis of HP1 gamma in HeLa lysates; NIH/3T3 lysates using HP1 gamma antibody.

Host or Source

Rabbit

Available Sizes

Curated Selection

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