Insulin Degrading Enzyme polyclonal antibody
Selected Variant
BZ16752-01
Size: 50 µL
Product Specifications
Background
This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Product Name Alternative
INSULYSIN; Insulin degrading enzyme; IDE
Swiss Prot
P14735
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human IDE
Conjugation
Unconjugated
Applications
WB, IHC-P
Dilution
WB: 1/500-1/1000 IHC: 1/50-1/100
Purity
Affinity Purified
Modification
Unmodified
Molecular Weight
Calculated MW: 118 kDa; Observed MW: 118 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of IDE in HepG2 lysates using Insulin Degrading Enzyme antibody.
Host or Source
Rabbit
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