Phospho-Glutamate Receptor 1 (AMPA Subtype) (Ser845) polyclonal antibody

Product Specifications

Background

AMPA- (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid), kainate-, and NMDA- (N-methyl-D-aspartate) receptors are the three main families of ionotropic glutamate-gated ion channels. AMPA receptors (AMPARs) are comprised of four subunits (GluR 1-4), which assemble as homo- or hetero-tetramers to mediate the majority of fast excitatory transmissions in the central nervous system. AMPARs are implicated in synapse formation, stabilization, and plasticity.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Product Name Alternative

GRIA1; GLUH1; GLUR1; Glutamate receptor 1; GluR-1; AMPA-selective glutamate receptor 1; GluR-A; GluR-K1; Glutamate receptor ionotropic; AMPA 1; GluA1

Swiss Prot

P42261

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human GluR1

Conjugation

Unconjugated

Applications

Dilution

WB: 1/500-1/1000

Purity

Affinity Purified

Modification

Phosphorylated

Molecular Weight

Calculated MW: 102 kDa; Observed MW: 102 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot analysis of Phospho-GluR1 in Human brain lysates treated with Lambda phosphatase lysates; Human brain lysates using Phospho-Glutamate Receptor 1 antibody.