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IL-1 Receptor Antagonist Protein polyclonal antibody

Product Specifications

Background

Interleukin-1 (IL-1) is a key pro-inflammatory cytokine that has diverse actions in the brain as a regulator of host defense responses and a mediator of inflammation. Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Product Name Alternative

IL-1 Receptor Antagonist Protein; DIRA; IRAP; IL1F3; IL1RA; MVCD4; IL-1RN; IL-1ra; IL-1ra3; ICIL-1RA

Swiss Prot

P18510

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human IL1RA

Conjugation

Unconjugated

Applications

WB, IHC-P, ICC/IF, IP, FC

Dilution

WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100

Purity

Affinity Purified

Modification

Unmodified

Molecular Weight

Calculated MW: 20 kDa; Observed MW: 20 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot analysis of IL-1RA in HeLa lysates; 3T3 lysates using IL-1 Receptor Antagonist Protein antibody.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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